Which hormone is primarily responsible for water reabsorption at the level of the kidney?

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Multiple Choice

Which hormone is primarily responsible for water reabsorption at the level of the kidney?

Explanation:
Arginine vasopressin (antidiuretic hormone) is the hormone that mainly controls water reabsorption in the kidney. It binds to V2 receptors on collecting duct cells, triggering a signaling cascade that inserts aquaporin-2 water channels into the apical membrane, increasing water permeability so water moves back into the bloodstream and urine is concentrated. Aldosterone manages sodium reabsorption (with indirect effects on water balance), while renin and erythropoietin serve other functions in fluid regulation and blood cell production, not direct water reabsorption.

Arginine vasopressin (antidiuretic hormone) is the hormone that mainly controls water reabsorption in the kidney. It binds to V2 receptors on collecting duct cells, triggering a signaling cascade that inserts aquaporin-2 water channels into the apical membrane, increasing water permeability so water moves back into the bloodstream and urine is concentrated. Aldosterone manages sodium reabsorption (with indirect effects on water balance), while renin and erythropoietin serve other functions in fluid regulation and blood cell production, not direct water reabsorption.

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